ABSTRACT
Rhinitis, characterized by inflammation of the nasal mucosa, is a prevalent condition affecting millions worldwide and even in our locality. It is often associated with bacterial infections. Understanding the antimicrobial susceptibility profile of anaerobic bacteria isolated from patients with rhinitis in the local population, is crucial for guiding empirical therapy, preventing antimicrobial resistance, and improving clinical outcomes.
The study evaluated patients from the Ear, Nose and Throat clinic of the University of Benin Teaching Hospital, Benin City. Patients data collected were age, sex, social history, medication history, rhinitis history, rhinitis symptoms, co morbidities and others. Patient specimen was collected using sterile swap sticks by the doctors and the collected specimens were isolated and identified and their antimicrobial susceptibility profile determined using disk diffusion and agar dilution methods.
With a total population of 41patients, 8 males (19.5) and 33 females(80.24%) with 36 anaerobic isolates. More participants were around the ages 21years to 25 years. Hence, more bacterial isolates were in this age range. There was no relationship between patient demographics and isolates. There were 15 Pseudomonas aeruginosa , 8 Bacillus subtilis, 6 Bacillus cereus, 2 Klebsiella pneumoniae , 4 Staphyloccoccus aureus. Microscopic analysis carried by gram staining, showed 3 groups of bacteria: gram positive bacilli, gram negative bacilli, and gram positive cocci.
In conclusion, patients demographics did not show any relationship with the isolates and five facultative anaerobes were identified and isolated; Bacillus subtilis, Bacillus cereus, Pseudomonas aeruginosa, Staphyloccoccus aureus, Klebsiella pneumonia. The isolates were more effective to the flouroquinolones with a minimum inhibitory concentration of 5ug.
