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ABSTRACT
Changes in thirst perception (TP), plasma osmolality (pOSM), plasma arginine vasopressin (pAVP) are all connected and are some of the physiological adaptations necessary against dehydration. This research aimed to investigate TP, pAVP, and pOSM following exercise in obese young adults. The study involved 20, apparently healthy adults aged 18-25 years and they were divided into 2 groups of 10 each. Group 1 comprised of normal weight individuals and group 2 were obese individuals. Participants received information about the objectives and procedures of the study. On the days they came to the laboratory, the participants were asked to drink 600 ml of water 2-3 hours before the exercise began to allow for optimal total body water content. The height and weight of the participants were determined using a stadiometer to determine BMI. After this, the subjects were asked to wait for a few minutes let's say 20-30mins to allow them to settle down and acclimatize to the laboratory conditions. Before starting the exercise, the various parameters were determined to establish baseline values. Subject were made to walk on a treadmill for 20 minutes, after which their TP and DM were determined by visual analog scale and blood samples were taken to determine pAVP and pOSM. Data were subjected to statistical analysis using Graph-Pad Prism version 8.1 statistical package and relevant statistical values were obtained. Student t-test was used and data was presented as mean ± SEM. Values of P<0.5 were considered statistically significant. Results showed that there was no significant change in TP, pOSM, DM and pAVP in obese individuals compared with normal weight, although, TP, pOSM, pAVP levels and DM post-exercise were increased significantly in obese individuals compared to pre-exercise. In conclusion, this research showed that following exercise, there was no change in TP, pAVP levels, plasma osmolality and DM in obese individuals when compared to normal weight.
