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ABSTRACT
Ginger is the substance which stimulates the specific defence systems of living organism by enhancing the resistance to pathogens during stressful periods. Growing evidence has linked WBC increase (Harold et al., 2018) to significant amount of ginger supplement. The aim of this study was to investigate the effect of ginger on white blood cells and differentials. 20 adult Wistar were employed for this study. The rats were randomly selected in four groups (n=5) with group A as control and the others as test groups. Group A (Control group): was fed with normal rat chow and water ad libitum while Group B, C and D received ginger (100mg/kg low dose, 300mg/kg medium dose and 500mg/kg high dose) respectively. After the experimental period, the rats were sacrificed and 5ml of blood was collected and taken to the laboratory for processing and analysis. A DH36 DYMIND was used for the assessment of a full blood count. Result were presented as mean plus or minus standard error of mean (SEM). Analysis of variance (ANOVA) was used to compare the mean of test and control value. The results showed no significant differences at low, medium and high doses compared with control for WBC, lymphocytes, granulocytes, however, observable differences were seen in the final body weight of the animals compared to the control. The present study revealed that the white blood cell count (WBC), lymphocyte count and MID count were not significantly different from those of control. white blood cell count (WBC), lymphocyte count did not show significant increase in rats on diets containing all doses (100, 300 and 500 gm/kg) of ginger. Final body weight was also reduced. This potentiates the immune function and obesity control of ginger.
