ABSTRACT

Intermittent fasting is any of various meal timing schedules that cycle between voluntary fasting (or reduced calorie intake) and non-fasting over a given period. It is not focused on what you eat but rather when you eat. Several studies have shown that intermittent fasting have various effects on factors such as weight loss, improved insulin sensitivity, and on cardiovascular health. The aim of this research is to determine the effect of intermittent fasting on Proaccelerin (Factor V) and haematological parameters. Sixty (60) apparently healthy adult individuals between the age range of 18 and 30 years were used for this research. Blood samples were collected from the participants twice. First during their normal eating routine and then after an intermittent fast  (12 hours) making a total of 120 samples used. The samples were analyzed using Enzyme linked immunosorbent assay (ELISA). The result showed a significant rise in white blood cell count. Lymphocyte and monocyte count were reduced. Granulocyte count was significantly increased. According to this study's on red blood cell metrics, intermittent fasting had no significant impact on hemoglobin levels, hematocrit values, or red blood cell count. MCH, MCHC and MCV also showed no significant difference in intermittent fasting compared with random intake of food. Platelet count showed no significant difference also. Proaccelerin (Factor V) level also showed no significant difference after intermittent fasting. In conclusion, this study revealed that no significant difference was observed in Proaccelerin level, MCH, MCHC, MCV, Platelet, haemoglobin, and haematocrit level. Monocyte and lymphocyte counts were significantly reduced; however White blood cell count and granulocyte level were significantly increased. This increase may be due to normal physiological response.