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ABSTRACT
Glucose serves as the body's main energy source for metabolism and is converted into glycogen, which is then stored in cells, through the actions of the hormone insulin. This study investigated the effect of glucose on tear production. 1gram of glucose was administered to a total of 45 subjects with mean age of 21.54±2.49 years were recruited for this study. These subjects were normoglycemic and free of ocular and systemic disease. This study was carried out at the University of Benin. Schirmer’s test was performed on this subject before and after the intake of glucose. The induced effects were checked at 30 minutes interval. The data gotten was analyzed using the statistical package for social sciences (SPSS) version 22.0. ANOVA. The result showed a slight decrease in tear production after 30 minutes (-2.91mm), further decrease was noticed at 60 minutes (-5.52mm), while a peak decrease was observed at 90 minutes (-7.39mm). The result showed a highly significant effect of glucose on tear production (p=0.000). The result was also analyzed using the unpaired t-test to compare the effect of orally administered glucose on tear production in both males and females. The result showed no significant difference between the effect of glucose on tear production in males and females (p>0.05). In conclusion, exhaustive case history is necessary for who report to the clinic with dry eye after the intake of a heavy carbohydrate meal within 90 minutes to prevent the misdiagnosis of dry eye.
