You have no items in your shopping cart.
ABSRACT
In both environmental and industrial contexts, Cadmium (Cd) is a pervasive contaminant known to induce oxidative stress through the generation of free radicals, leading to various forms of kidney damage, including proximal tubule and glomerulus dysfunction. Recently, the nutritional significance of Cocos nucifera L. water has surged due to its unique physiochemical composition, making it a sought-after beverage with therapeutic potential. This study investigates coconut water's potential protective effect against cadmium-induced kidney toxicity. Male Wistar albino rats (20, weighing 165±21.78g) were categorized as follows: Group A received 2 mg/kg body weight of cadmium alone, Group B received both cadmium (2 mg/kg body weight) and 4 ml/kg body weight of Cocos nucifera L. water, Group C received cadmium (2 mg/kg body weight) and 6 ml/kg body weight of Cocos nucifera L. water, and Group D (control) received only Cocos nucifera L. water. Histopathological examinations revealed that Cocos nucifera L. water mitigated Cd's adverse effects and maintained renal tissue's typical structure. Additionally, it effectively suppressed lipid peroxidation and restored depleted antioxidant defences in the renal tissue caused by Cd exposure, primarily through its antioxidant properties. These findings suggest that Cocos nucifera L. water may offer nephroprotection against Cd-induced toxicity, potentially optimizing outcomes in Cdinduced nephrotoxicity cases."
