You have no items in your shopping cart.
ABSTRACT
High-fructose corn syrup (HFCS) has made sugar intake easy, leading to different health risks. Fructose, the sweetest naturally occurring carbohydrate, is predominantly metabolised in the liver, replenishing hepatic glycogen and generating triglycerides. This study assessed the effects of cellgevity on male Wistar rats given with a high sugar diet. cellgevity, a poly-antioxidant substance, is said to contain potential therapeutic qualities for metabolic diseases. Twenty (20) male Wistar rats weighing an average of 200grams each were randomly divided in four groups of five. The rats were fed ad-libitum with the diet and clean tap water over the full period of the experiment. A basal diet of a regular pelleted grower’s mash was supplied to the control group (group1), whereas 60% high fructose food together with 10% fructose water was fed to the other three cages. Atorvastatin was provided regularly to group 3 and cellgivity was administered to the rats in group 4. The therapy was administered by an oro-gastric gavage. Using established methods, the weekly weight of the rats, their daily food consumption, feed efficiency, and the relative organ weight of the heart, liver and kidney were determined. The data was evaluated using the one-way analysis of variance (ANOVA), followed by Tukey’s test of significance. A p value of less than 0.05 (p<0.05) was recognised as statistically significant (p<0.05). The results of the study revealed that the cellgevity significantly lowered (p<0.05) the levels of Hs-CRP, MDA; but, increased the level of TAC when compared to the negative control group. There was no statistically significant difference (p<0.05) between the outcomes of the cellgivity group and the positive control group. The findings from this study reveal that cellgevity can be stated to be a good antioxidant supplement for the prevention and management of inflammation.
