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ABSTRACT
The search for novel lead chemicals in the pharmaceutical sector and the fight against diseases both benefit greatly from the use of medicinal plants. The exploration of these plants' potential as phytotherapeutics begins with research into ethnomedical claims made about them. Justicia secunda is a medicinal plant used widely which is reported to have diverse functions, including blood-boosting potential. This study therefore aimed at finding the potential anti-anaemic effect of the aqueous extract of Justicea secunda leaves in phenylhydrazine (PHZ) induced-anaemia albino rats on haematological parameters. The experimental animals were randomly grouped into five groups of six rats each; group 1 (non-anaemic control), group 2 (anaemic control), group 3 (190mg/kg bw of J. secunda extract), group 4 (380mg/kg bw of J.secunda extract) and group 5 (200mg/kg bw of ferrous sulphate). PHZ was administered once at a dose of 80 mg/kg bw to induce anaemia. After 28 days of extract administration, they were humanely sacrificed and the serum collected was used for Full blood count using SFRI autohaematological analyser, Peripheral blood film by Leishman staining and reticulocyte count using new methylene blue.
