You have no items in your shopping cart.
ABSTRACT
Bacteria can be resistant to multiple antibiotics and we are fast approaching a time when antibiotics will not work on some bacterial infections. New antimicrobial compounds are urgently necessary. Indole is an aromatic heterocyclic compound containing a benzene ring fused to the pyrrole ring in the second and third position of the pyrrole ring. Indole is an important heterocyclic system because it is built into proteins in form of amino acid.A large number of indole moieties have been investigated in the development of new efficient bioactive molecules with diverse pharmacological properties, such as antimicrobial, antiviral, anticancer, anti-inflammatory, inhibitors, and antioxidant. Generally, indoles substituted at 2nd or 3rd position, are known to exhibit certain bioactivity. The study is aimed at synthesizing and physically characterizing indole-3-carboxylic acid and indole-3-carbinol. The compounds were synthesized using the Vilsmier-Haack formylation and characterized with respect to the melting point and solubility. The synthesized compounds showed considerable properties. Therefore, the synthetic approach used is highly recommended because of its economic feasibility.
