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The 2019 to 2021 coronavirus pandemic was caused by an illness that was initially discovered in December 2019 in Wuhan, the capital of China's Hubei province. Since then, the disease has spread around the world. In order to stop the virus's spread in 2020, there were significant lockdowns in numerous cities throughout the globe. The influence of Covid-19 on the world has made it more important than ever to evaluate illness surveillance techniques among young people, especially in universities. This study was conducted to determine the seroprevalence of SARS-CoV-2 antibodies amongst the students of the faculty of management science, University of Benin. A cross sectional study was conducted and data was collected using the Open Data Kit (ODK) app to allow for real time transmission and monitoring of the data quality. For the detection of IgM, the STANDARDTM Q COVID 19 IgG/IgM combo test (SD Biosensor) was used. The manufacturer reports a specificity of 96.94% (95/98, 95% CI, 91.31% -99.36%) after 14 days after symptoms onset. The mean age of all the students that partook in this study was 21.5 years old (±2.6). 274 (46.6%) students that answered the questionnaire were male students, and 315 (53.2%) were female students, out of all the participants. 127 (21%) of the students that participated in the study live continuously in Lagos state, while 290 (49.1%) live in Edo state. The majority of the students that partook in this study had live primarily in Edo state. Of the 41 students in the faculty of Management science, University of Benin tested for IgG 10(37.0%) females tested positive for IgG and 17(63.0%) males tested positive for IgG. Students in this faculty that tested for IgG reported their age to be between 18 – 21: 23(56.1%), 22 – 25: 17(41.5%) and ≥26: 1(2.4%). There is no also significant association between the negative IgG and their age as indicated by a p-value of 0.766. Forty-four 28 students representing 68.3% of the students in the faculty of management science had no problems wearing face mask another 13 students representing 31.7% said they were not comfortable wearing a facemask. This cross-sectional study shows that there is a high SARS-CoV-2 seroprevalence amongst the students of the faculty of management science and the university of Benin. This held true despite the varying sociocultural characteristics, ages, sex, housing, and residence of the students both during and after session in all of the surveyed university's faculties.
