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ABSTRACT
Infertility refers to an inability to conceive within one year duration of regular unprotected sexual intercourse. Male infertility has been attributed to a variety of causes including lifestyle factors, hormonal dysfunction, testicular failure, ejaculatory disorders and obstruction. Evaluation of male infertility is important to identify a cause and provide treatment of the etiology if correctible. This research examine seminal germ cells and some biochemical profiles of male infertility in Benin Metropolis, Edo State. One hundred subjects consisting of 47 azoospermic and 53 Oligospermic patients from St. Augustine Medical Centre and 100 apparently healthy Normospermic individuals as control were used in this study. Quantitative measurement of hormonal profiles were determined by Enzyme- linked immunosorbent assay (ELISA). Nutritional profiles consisting of cholesterol, triglyceride, total protein, globulin, albumin and fasting blood sugar were determined by colorimetric method. The mean levels of prolactin, FSH and LH were significantly higher (P < 0.05) while mean levels of testosterone was significantly lower (P < 0.05) in azoospermic than control subjects. The mean level of testosterone was lower (P < 0.05) in oligospermia but no significant differences were observed in the levels of LH, FSH and prolactin when compared with the controls. Similarly, no significant difference was observed in the levels of cholesterol, triglyceride, total protein, and albumin among infertile men than control subjects. However, fatty glucose was significantly higher (P < 0.05) among azoospermia than controls. Hormonal imbalance is common among infertile males used in this study.
