You have no items in your shopping cart.
ABSTACT
Cancer starts when cells in the body starts to grow out of control (malignant growth). Colorectral cancer starts in the colon or the rectum. Annona Muricata is a medicinal plant and is considered as a basis for health preservation and care worldwide. Degenerative diseases have reached epidemic proportions and are considered as a serious health problem, therefore treatment of these diseases are of clinical importance. 1,2 dimethylhydrazine induced colon cancer in rats. The rats were randomly allocated into six groups: control, extract alone, DMH, extract and DMH together, extract before DMH, DMH before extract. DMH was injected subcutaneously at 25mg/1000g body weight once a week for 14 weeks, while Annona Muricata extract was administered to rats orally at 120mg/1000g. After sacrifice, colon and liver sections were dissected out for histological and some biochemical analysis. Results shows that the group injected with DMH (subcutaneously) and orally administered leaves extract of A. Muricata showed similar result with the rats fed with normal feed, as there was absence of polyps in the colon of these rats when compared to those injected with DMH alone for 14weeks. From the findings of this result it shows that ethanol extract of A. Muricata leaves has a prophylactic effect on 1,2, dimethyl hydrazine (DMH) induced colon, rectal and liver cancer and can also be used in the treatment of DMH induced existing cancer.
