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ABSTRACT
The goal of the investigation was to examine the growth hormone (GHR) gene polymorphism and its morphometric expression in various goat breeds. The investigation was conducted at the University of Benin's Farm Project's Rabbit unit in Benin City. Blood samples from 5 different goat breeds, including WAL, WAD maradi, red sokoto, and crossbred WAL and red sokoto, were used for the analysis. The results shows the position and sequence of polymorphism and morphometric parameters. This research investigates the polymorphism of the growth hormone receptor (GHR) gene and its potential correlation with morphometric traits in a specific population. A sample of individuals was genotyped for GHR gene variations, and their morphometric data, including height, weight, and other relevant measurements, were collected. Statistical analyses revealed associations between certain GHR gene polymorphisms and variations in morphometric traits. These findings contribute to our understanding of the genetic underpinnings of growth-related characteristics and may have implications for personalized medicine and livestock breeding programs. The growth hormone receptor (GHR) gene plays a crucial role in mediating the effects of growth hormone (GH) in humans and other mammals. Genetic variations within the GHR gene have been associated with diverse physiological and morphological characteristics. This study aimed to explore the polymorphisms within the GHR gene and investigate their potential associations with morphometric traits in a well-defined population. Genomic DNA was extracted, and specific regions of the GHR gene were genotyped using advanced molecular techniques. Morphometric data were collected, including measurements of height, weight, body mass index (BMI), and other relevant traits. The analysis of GHR gene polymorphisms revealed a range of genetic variations within the study population. Through statistical analyses, we identified significant associations between certain GHR gene polymorphisms and specific morphometric traits. For example, individuals carrying a particular GHR variant exhibited a statistically significant increase in height compared to those with a different variant. Similarly, other GHR polymorphisms were associated with variations in weight and BMI.