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ABSTRACT
Obesity is a medical condition in which excess body fat has accumulated to the level that produces a negative effect on our health. Obesity is defined as a Body Mass Index (BMI) of 30kg divided by height in meters squared (Kg/M²) or above. Obesity and uncontrolled body weight gain is associated with many chronic diseases and can reduce life expectancy. Plasma prothrombin also known as Factor II is a coagulation protein and refered to as serine. Prothrombin time is a test that characterise blood coagulation. Prothrombin time is the time in seconds for a patient's plasma to clot after the addition of calcium and an activator (thromboplastin). The aim of the study was to investigate the effects between high body mass index(obesity) and plasma prothrombin time values in young female adults ages 18-30. Obese adults within the age range of 18 and 30 years were recruited in the study. Sixty (60) subjects were enrolled for the study. Thirty (30) moderately obese subjects and thirty (30) non-obese subjects used as control. 4.5mls of whole blood was collected and dispensed into 0.5ml sodium citrate bottles for coagulation studies. There was a significant difference in BMI of obese and control while PT showed a decrease though not statistically significant between the obese and non-obese subjects. In conclusion, prothrombin time PT in obese subjects are shorter than the control group.
