You have no items in your shopping cart.
ABSTRACT
Traditional medical practice has been an integral part of indigenous populations in many parts of the world. Psidium guajava (guava) leaves have been used traditionally to manage several diseases. The aim of the study was to determine the phytochemical quality and antibacterial activity of Psidum guajava leaf extract. The leaves were obtained from the Botanical Garden, University of Benin, Benin City and extraction was carried out with water and ethyl acetate. The presence of the phytochemicals was determined qualitatively using standard methods. Both aqueous and ethyl acetate extracts were screened for antibacterial activity against Staphylococcus aureus (20/22mm), Enterobacter sp. (12/00mm) Klebsiella sp. (00/00mm), Salmonella sp. (14/14mmmm), Pseudomonas aeruginosa (25/20mm), Bacillus subtilis (14/14mm ) and Escherichia coli (13/14mm). The antibacterial activity was determined by agar-well diffusion method and expressed as the diameter of the zone of inhibition of bacterial growth around the wells. Both the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were carried out through the agar-dilution method. Results obtained from the phytochemical screening revealed the presence of terpenoids, steriods, alkanoids, flavonoids, eugenols and the absence of saponins, phenols, tanins, reducing sugars and glycosides.
