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ABSTRACT
Toll-like receptors (TLRs) are an important family of receptors that constitute the first line of defense system against microbes. They can recognize both invading pathogens and endogenous danger molecules released from dying cells and damaged tissues and play a key role in linking innate and adaptive immunity. TLRs are widely distributed in both immune and other body cells. The experiment was carried out to investigate the effect of toll like receptor 2 in different rabbit breed. The experiment was conducted in the university of Benin livestock farm and a total of 40 animals from 4 breeds of rabbit was used for this experiment. The breeds include Newzealand, Dutch, Hyla white and chinchilla. Blood samples were collected using DNA, and RNA plain shield collected in a plan bottle from the marginal ear vein, to see the phylogeny of toll like receptor 2 in rabbit. It was put into vascutainer tubes containing Ethylene-diamine-tetra-acetic acid (EDTA) as Anticoagulant using sterile Needle. Six(6) blood samples were collected from chinchilla male parent F1 generation Cross bred (CHxNZB) male, Hyla female parent, F1Hyla male F1 Dutch male, and Newzealand black male parents and it was taken to the laboratory for analysis in Inquaba Biotechnology west Africa Ltd, ibadon oyo state awaiting the results.
