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ABSTRACT
Haemostasis is the arrest of blood flow and control of haemorrhage from an injured blood vessel. It involves a series of cellular and biochemical events that function together to keep blood in the liquid state within the veins and arteries and prevent blood loss following an injury to the blood vessels through the formation of a blood clot. The systems involved in the haemostatic process include the vascular system, coagulation system, platelets and fibrinolytic system (Hoffmeister, 2001). Obesity is the abnormal or excessive fat accumulation that presents a risk to health, it is a well known risk factor for clots in deep veins and can also cause pulmonary embolism leading to sudden death or strain on heart. The aim of this study is to investigate a possible obesity induced disorder on some haematological and haemostatic profiles and possibly reduce the risk of development of chronic diseases early in life amongst young females in the University of Benin, Benin city, Edo, Nigeria. A total of one hundred and twenty young females (subjects) were recruited from the population of the university of Benin. The 120 subjects were divided into two categories with the aid of WHO classification of obesity i.e. subjects with BMI ≥ 30 as test obese subjects and subjects with BMI ≤ 29 as test control subjects. 10mililitres(10mls) of blood sample collected from each subject (5mls into EDTA container for haematological tests and 4.5mls of whole blood into container with 0.5ml Sodium citrate for Prothrombin Time test, Activated Partial thromboplastin Time test and Fibrinogen Assay).
