MOLECULAR DOCKING OF THE ACTIVE COMPOUNDS PRESENT IN DICHLOROMETHANE FRACTIONS OF Uraria picta AGAINST MATRIX- METALLOPROTEASE- 2 INHIBITOR

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ABSTRACT

Molecular docking is an essential technique used in the production and development of new drugs. The Dichloromethane Extract from Uraria picta that yielded the three phytochemicals used in this study were utilize for their anti-fibriod properties. After the end of the molecular docking process between the three ligands and the target protein (MMP-2 inhibitor) , the results reveals that Kaempferol was the best phytochemical to reduce the activity of MMP-2 Inhibitor since it has the lowest binding affinity.

 

 

 

 

 

 

 

 

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