LIPID PROFILE OF BLOOD PRESERVED IN GLYCOSAMINOGLYCANS

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ABSTRACT

If consistent amounts of numerous analytes, including lipid profile, are sought, sample stability is essential. Determining the impact of the separated anticoagulant from a plant base source on the  lipid profile was the aim of this investigation. For four (4) weeks at room temperature, the levels of triglycerides, high density lipoprotein, and   low-density lipoprotein were measured.

There was a decrease in the concentrations of cholesterol (165±0.63 to 157±0.63), triglycerides (143.5±1.08 to 135±0.64), and low density lipoprotein (85±1.03 to 75±2.16), this may be caused by Lipoprotein Lipase's interaction with the isolated anticoagulant, the high density lipoprotein (48±1.63 to 54±0.41) levels increased in concentration. All of the measured parameters were discovered to be within the typical clinical values. The tests have effectively demonstrated the potential for a plant-based anticoagulant as a substitute for heparin made from animals. Due to LDL ("bad") cholesterol's propensity to encourage the creation of plaque accumulation in the arteries (atherosclerosis), which causes heart attacks, lipid profile measurements are now nearly standard tests for predicting cardiovascular risk. The therapy of cardiovascular disorders may hold significant promise for the isolated anticoagulant.

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