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The goal of this investigation was to separate Escherichia coli from wastewater in the hostels operated by UNIBEN. After serial dilution, the total bacterial count of the waste water samples was ascertained using standard bacteriological techniques using pour plate methods. Morphological and biochemical techniques were employed to characterize and identify the bacterial isolates. A statistical method was used to assess the isolates' frequency and percentage distribution. The study's findings demonstrated that the wastewater used in the investigation had a bacterial population that varied from 2.50 log10 cfu/ml to 3.10 log10 cfu/ml. Enterobacter cloacae, Klebsiella pneumonia, Escherichia coli, and Serratia marcescens were the isolates acquired in this investigation. The lipase and gelatinase pathogenic pathogenicity tests yielded good results for the isolates. Methronidazole, erythromycin, tetracyclin, and gentamycin were resistant to the isolates, however they were susceptible to augmentin, ciprofloxacin, clindamycin, and collistin. Additionally, all of the isolates in this investigation had multiple resistance indices of 0.56, which is higher than the advised 0.2. To effectively manage wastewater and protect water quality, it is imperative to have knowledge about these organisms found in waste waters and the potential health risks they provide to the public.