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ABSTRACT
Blood act as a pathological reflector of the status of the exposed animals to toxicants and other conditions. The examination of blood provides the opportunity to clinically investigate the presence of metabolites and other constituents in the body of humans and it plays a vital role in the physiological, nutritional and pathological status of an animal. Blood constituents change in relation to the physiological status of an individual. These changes are important in assessing the response of individuals to various physiological situations. These changes are often caused by several factors; some of which are genetic and others, non-genetic. Age, sex and management systems are among the factors that influence blood-based parameters of some persons. It is important to establish baseline indices for these parameters on the basis of these factors and determine the effects of these factors on these indices. Obesity is a medical condition in which excess body fat has accumulated to the level that produces a negative effect on our health and changes in hematological parameters. Obesity and uncontrolled body weight gain is associated with many chronic diseases and can reduce life expectancy. The aim of the study was to investigate the association between high body mass index(obesity) and hematological parameter levels in young female adults ages 18-30. Obese adults within the age range of 18 and 30 years were recruited in the study. Sixty (60) subjects were enrolled for the study. Thirty (30) moderately obese subjects and thirty (30) non-obese subjects used as control. Five(5) ml of whole blood was withdrawn from all participants through the antecubital fossa and into EDTA container. The blood was taken to the hematology department laboratory of the University of Benin Teaching Hospital for analysis.The results showed an increase in the BMI of obese subjects, with a significant difference in obese compared with non-obese individuals (p<0.05). Data was analyzed graph pad statistical software version 8.1. and results analyzed were presented in mean +/-SEM. Student t-test was used to compare the dependent and independent variables. P-value less than 0.05 was considered statically significant. In conclusion, subjects with obesity had no significantly higher value of hemoglobin and red blood cell count when compared with normal weight subjects, this implied that weight gain does not affect hematopoietic processes.
