ABSTRACT

The capacity of probiotic bacteria to adhere to different surfaces is one of the most important aspects in choosing them. Since Lactobacillus species are widely distributed in the microbiota of humans and animals, particularly in the reproductive and digestive systems, lactic acid bacteria are frequently selected for their probiotic qualities. Drugs that are weakly soluble are made more soluble by using solubilizing agents. This study aims to investigate the mechanism of action of Polyethylene glycol 300 (PEG300) in the effective removal of Lactobacillus rhamnosus, gasseri, and reuteri from adsorbents. PEG300 solutions were made at different concentrations (100%, 75%, 50%, 25%, 12.5%, 0%) to test how well they could desorb various lactobacillus species from hardened albumen and egg membrane. According to the results obtained,The best desorption of Lactobacillus gasseri from solidified albumen was obtained at a 50% concentration of PEG300, whereas the best desorption of Lactobacillus gasseri from egg membrane was obtained at a 12.5% concentration