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ABSTRACT
Obesity is a medical condition in which excess body fat has accumulated to the level that produces a adverse effect on our health. It measured by BMI (body mass index), obesity is considered when the BMI is >30kg/m2 . It increases the risk of coronary heart disease, diabetes mellitus and cancer. The aim of this study is to assess the effect of obesity on plasma level of Factor v in obese and non-obese subjects. Obese adults within the range of 18-30 years were recruited for this study. Sixty subjects were used to carry out this investigation, Thirty(30) moderately obese subjects were used for the study against Thirty(30) nonobese as control. 4.5ml of whole blood was collected and dispensed into 0.5ml sodium citrate bottles for coagulation studies. The result showed an increase in BMI of obese subjects, with a significant increase in test compared to non-obese subjects( p<0.05). in conclusion, the BMI increased when compared with control due to an increase in adipose tissue mass leading to increase in body mass. Subject with obese has a significantly high value of proaccelerin level in plasma when compared to normal weight subjects. This implies that obese subjects coagulates faster than normal subjects.
