ABSTRACT
The evolution of human culture depends critically on the use of medicinal plants, all tribes and civilizations use medicinal plants as a source of treatment. Salvia hispanica, popularly known as chia, is an annual herbaceous plant. It belongs to the Salvia genus, Labiate mint family, and Nepetoideae subfamily of the Lamiales order. According to research, the hypotensive, hypoglycemic, antibacterial, and immunostimulatory properties of chia seed components are credited with helping to enhance blood lipid profiles.Chia seeds include a large number of phenolic components, active ingredients, and essential fatty acids. The active ingredients are myricetin, kaempferol, quercetin, Gallic acid, caffeic acid, Ferulic acid, etc. The aqueous and ethanolic extract of Salvia hispanica was used to carry out the study following High performance liquid chromatography(HPLC) and bioinformatics analysis, which was used to discover the most abundant phytochemical present In salvia hispanica. The abundance of Quercetin as seen in the study showed that salvia hispanica is rich in phytochemicals and has medicinal potentials. For the bioinformatics study, the molecular docking results disclosed that Quercetin followed by kaempferol showed favorable binding affinities with α-amylase, α-glucosidase and pancreatic lipase. Quercetin is an abundant phytochemical compound which proved to be of so much medicinal benefits as it helps in scavenging free radicals and reducing the oxidation of lowdensity lipoproteins. It acts as an anti-inflammatory agent as well as antioxidant thus helping to reduce inflammation. It also has low binding affinities which means that it acts as therapeutic drug and used in certain medical treatment.
