You have no items in your shopping cart.
ABSTRACT
The evolution of human culture is critically dependent on the use of medicinal plants. Nearly all tribes, clans and civilizations use medicinal plants as a source of treatment. Tetrapleura tetraptera popularly known as 'Aridan', a plant native to West Africa, is a leguminous deciduous plant. It belongs to the Tetrapleura genus, Fabaceae family and Caesalpiniodeae subfamily of the Fabales order. According to research, the Antidiabetic, antioxidant, anti-inflammatory antimicrobial, antipancreatic lipase, and antimalarial properties of Tetrapleura tetraptera components are credited with helping to migigate insulin resistance. HPLC was carried out on the Saponins and Alkaloids of T. tetraptera. Thereafter, the phytochemicals with highest concentration were used for docking on α-amylase, α-glucosidase, and pancreatic lipase. The abundance of Aesculetin as seen in the study showed that T. tetraptera is rich in phytochemicals and has medicinal potentials. For the bioinformatics study, the molecular docking results disclosed that Naringenin followed by Butein and Serotonin showed favourable binding affinities with α-amylase, α-glucosidase and pancreatic lipase. The chemicals found in T. tetraptera have been found to possess potential inhibitory activity with α-amylase, α- glucosidase and pancreatic lipase.
