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ABSTRACT
This work focuses on the extraction, phytochemical screening and characterization of methanol extract of Datura metel (purple thornapple). Extraction was carried out with the use of a Soxhlet extactor using methanol as the extraction solvent. Percentage yield of the extract was 19.22%. Phytochemical screening of the extract indicated the presence of glycosides, alkaloids, eugenols and flavonoids. Saponins and terpenoids were largely present. Thin layer chromatography (TLC) analysis showed that methanol had the highest retention factor when compared with other solvents, hence making it the most suitable for this extraction process. Characterization was carried out with High Performance Liquid Chromatography (HPLC). Results of this analysis indicated an abundance of some important constituents namely; Scopolamine, Atropine, Quercin and Beta-caryophyllene, with Scopolamine having the most abundance.