ABSTRACT
Emilia coccinea is a plant that is used in folk medicine to treat a variety of conditions, including tumours, inflammation, cough, rheumatism, fever, microbial infections, diarrhoea, wounds, eye inflammations, night blindness, earaches, and miscarriage prevention. In order to confirm Emilia coccinea leaves' alleged traditional use in treating microbial illnesses, the assessment of the leaves' ethyl acetate fraction was done.
Agar well diffusion technique was used to determine the sensitivity tests for the aerial portion of the fraction's antifungal properties/activities. Using Agar dilution, the minimum inhibitory concentrations (MICs) of fractions were also calculated. To assess the sensitivity of the tested organisms, antifungal medication (Ketoconazole) was employed as a positive reference standard. The ethyl acetate fraction was shown to be sensitive to the test organisms (Candida albicans, Trichophyton rubrum, and Rhodotorula glutinis), but not to Aspergillus fumigatus and Microsporum audounii.
The maximum mean inhibition diameter against Candida albicans was 13.25 ± 0.27 mm at 100 mg/ml for the ethyl acetate fraction.
According to the findings, E. coccinea plant exhibits antifungal activity against some fungal isolates and may serve as a source of antifungal drugs. Therefore, the traditional use of this herb to treat microbiological infections is supported.
