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ABSTRACT
Hunteria umbellata is a plant species known for its medicinal properties. The purpose of this study was to evaluate the anti-convulsant effect of methanolic seed extract of Hunteria umbellata through maximal electro-shock model in mice. The animals used in this study were grouped into five. Group I acted as the control and was administered distilled water, group II, III, IV respectively received 250 mg/kg, 500 mg/kg and 1000 mg/kg dose of the methanolic seed extract and group V received the standard drug Phenobarbitone. At the end of the study, percentage protection was recorded. The result obtained from this investigation suggested that methanolic seed extract oof Hunteria umbellata possessed no significant anti-convulsant effect in Maximal Electro-Shock (MES) induced convulsion but a dose-dependent recovery rate with the treatment group administered the highest dose (1000 mg/kg) showing the quickest recovery time and the lowest dose (250 mg/kg) the slowest recovery time. In conclusion, it is suggestive the plant extract possess no anti-convulsant property.
