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ABSTRACT
Antibiotic-resistant bacteria have emerged due to the selective pressure of antimicrobial use in humans and animals. Water plays an important role in dissemination of these organisms among humans, animals and the environment.Escherichia coli comprises Gram-negative, fecal-borne pathogenic and commensal bacteria that are frequently associated with antibiotic resistance. AMR E. coli can be ingested via food, water and direct contact with fecal contamination.The present study was carried out to determine the effect of lead on antibiotic resistant Escherichia coli from water. In this study E. coli was isolated from two water samples, one with lead and the other without lead. A total of 2 samples were then examined (isolate 16 and 17). Characterization of antimicrobial resistance, multiple antibiotics resistance (MAR) index and various biochemical tests were carried out. The results revealed that isolate 17 (E. coli treated with lead chloride) proliferated much slower compared to isolate 16 (E. coli only). Isolate 16 was resistant to all antibiotics used while isolate 17 was resistant to eight. All isolates revealed high multi antibiotic resistance index (> 0.2).
