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ABSTRACT
The present study aimed to assess the effect of water pollution on physiological and histological alterations of Mudfish (Clarias anguillaris) collected from November 2021 to March 2022. Results showed significant differences (p≤0.05) in all estimated physicochemical environmental factors in study areas. The study assessed two(2) different sites of Ikpoba River. A total of fifty two fish was collected from the three different sites every week for twelve (12) weeks and known weight of the brain and gills were recovered for enzyme assays. The study recorded decreased organ weights and lactate dehydrogenase(LDH) activity in the tissues/organs of fishes in different site-exposed fish species when compared with control. Fishes from Guinness site contained the highest level of LDH activities when compared with capitol site. The study shows an increased deterioration of Ikpoba River and suggests that high metal content caused oxidative stress in fishes which manifested as alteration of energy biomarkers. According to current study, the waste should be treated before being dumped into water ways.
