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ABSTRACT
This study is informed by the need to examine the elemental interactions and synergistic effects of a polyherbal mixture in the treatment of gum-related toothache. The plants selected are welldocumented for their analgesic, anti-inflammatory, antibacterial, and wound-healing properties. The research involved phytochemical analysis, antimicrobial assays, and elemental composition studies. Antibacterial susceptibility testing showed the gram-negative bacteria were more resistant to the extract than the gram-positives. Such significant zones of inhibition, with P. aeruginosa recording the least IZDs, while L. acidophilus recorded the highest IZDs, indicating strong antimicrobial synergy among the polyherbal extracts. Furthermore, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) assays confirmed the efficacy of the combined extracts in eradicating bacteria pathogens at relatively low concentrations, with the result recording the lowest MIC and MBC values against L. acidophilus, while P. aeruginosa recorded the highest values. Quantitative phytochemical analysis and elemental composition studies revealed the presence of essential minerals and antioxidants that contribute to oral tissue healing and pain relief. Though further research is required, the study proposes that the polyherbal mixture offers a natural, safe, and effective alternative to synthetic medications for the treatment of gum-related toothache.
