EFFECTS OF DIET ON ANTIMICROBIAL RESISTANCE OF FAECAL Escherichia coli AMONG STUDENTS OF A TERTIARY INSTITUTION IN BENIN CITY, NIGERIA

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ABSTRACT

The increasing prevalence of antimicrobial resistance (AMR) poses a significant global health threat, particularly in developing countries where dietary habits and antibiotic misuse are widespread. This study investigates the effect of diet on the antimicrobial resistance profile of Escherichia coli isolated from the fecal samples of students in a tertiary institution in Benin City, Nigeria. A cross-sectional study was conducted among students, with participants completing dietary surveys to categorize their eating habits. Fecal samples were collected and analyzed to isolate Esherichia coli which were then subjected to antimicrobial susceptibility testing using the disk diffusion method. Data on dietary patterns and resistance profiles were statistically analyzed to identify potential associations. The findings revealed that Multiple antibiotic resistance (MAR) index was significantly higher (p = 0.0162) in males (0.96 ± 0..07) compared to females (0.90 ± 0.11). This is possibly due to antibiotic not being regulated in this clime. Age, faculty and year of study did not affect Multiple Antibiotic Resistance (MAR) index ( p > 0.05). Majority of participants consume the same kind of food/fruits. Eating fast food was not significantly (p > 0.05) associated with antibiotic resistance.

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