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ABSTRACT
The seed of avocado is considered as one of the non-edible part of the fruit, which are usually discarded as residues and can cause ecological problems. Exploring the possible dietary and therapeutic potentials of such underutilized wastes will help to reduce the possible environmental waste burden. According to several studies, the hypolipidemic effects of the avocado seed focused on methanolic extracts and aqueous extracts. The result shows that, hypolipidemic effects provides an interesting alternative since the seed represents 13-18% of the avocado fruit and is discarded during avocado pulp processing. It has been stated that, uses of avocado pear seed include use in the management of hypertension, diabetes, cancer and inflammation. The purpose of this study was to investigate the effects of aqueous extract of avocado seed on the kidney of adult wistar rats. In the experiment, twenty adult Wistar rats were randomized into four groups (A - D). Group A was control that received only feed and water. Group B received a dose of 500mg/kg body weight of the extract. Group C received 1000mg/kg body weight of the extract. Group D received 1500mg/kg body weight of the extract. The rats were fed with mash and water for the experimental period that lasted for 28 days. At the end of the treatment period, the rats were anaesthetized using chloroform.
