EFFECTS OF AQUEOUS EXTRACT OF SOYBEANS (Glycine max)

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ABSTRACT

Mercury chloride (HgCl2) is a toxic heavy metal compound known to induce various detrimental effects on biological systems. The cerebrum is the largest and most complex part of the human brain. It plays a pivotal role in various cognitive functions, such as memory, perception, and higher-order thinking processes, and is comprised of distinct regions involved in specific tasks. Soybean (Glycine max) is a versatile and economically significant leguminous crop that holds a central role in global agriculture, known for its high protein content and wide-ranging applications. It is also known to have antioxidants, anti-inflammatory, antidiabetic, and neuroprotective functions. This study aimed to investigate the potential effects of an aqueous extract of soybeans on mercury chloride-induced neurotoxicity in adult Wistar rats. Twenty-four adult Wistar rats were randomized into four (4) groups consisting of six (6) rats each. Group A served as control and received 1ml of distilled water daily to compensate for stress of administration, group B received 4mg/kg body weight of mercury chloride, group C received 1000mg/kg body weight of aqueous extract of Glycine max daily and group D received 1000mg/kg body weight of aqueous extract of Glycine max 1 hour before 4mg/kg body weight of mercury chloride.

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