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ABSTRACT
Herbal medicine serves as a global spokesperson for the most significant areas o f conventional medicine.To support the appropriate use of herbal medicine and t o ascertain the plants' potential as a source of novel pharmaceuticals, research o n medicinal plants is crucial.The world health organization (WHO) estimates th at over 80% of people on the planet rely on traditional medicines to meet their b asic medical needs.It also made suggestions for advancing the technology used i n the production of therapeutic plants.This study's main goal is to methodically l ook at how Moringa oleifera affects adult Wistar rats' spleens.24 adult Wistar ra ts weighing between 150 and 220 grams were divided into four groups at rando m, with six rats in each group. animals. The experimental animals were acclimatised under proper environmental condition. Plastic cages were used to house the animals, with six rats per cage. All experimental animals had free access to feed and clean water during the course of the study. Group A Control group - Feed and water only. Group B was administered with 200kg/mg body weight of aqueous extract of soursop (Low dose). Group C was administered with 400mg/kg body weight of aqueous extract of soursop (Intermediate dose). Group D was administered with 800mg/kg body weight of aqueous extract of soursop (High dose). The administration was done orally for twenty-eight days. The animals were sacrificed under chloroform anaesthesia; a midline incision was made through the ventral wall of the abdomen of the rats. The spleen was removed and fixed in formal saline for histological analysis. Discoveries in this explore shown that fluid extricate of Moringa oleifera played a part in expanding or progressing splenic capacities - Cell sequestration and lymphoid follicle actuation.
