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ABSTRACT
This study investigates the impact of edible clay consumption on maternal health parameters, specifically lipid profile across the three trimesters of pregnancy in Wistar rats. Despite its traditional use in various cultures during pregnancy, scientific evidence regarding its effects remains limited. The research aims to assess the influence of edible clay on maternal lipid profile parameters, including total cholesterol, triglycerides, high-density lipoprotein cholesterol (HDLC), and low-density lipoprotein cholesterol (LDL-C) throughout pregnancy. The selection, acclimatization, and grouping of forty-eight healthy female Wistar rats are described, along with the administration regimen for different experimental groups. The experiment was conducted over a period of 20 days, with lipid parameters measured at 10-day intervals. Results revealed that after 10 days of administration, there were no significant differences in total cholesterol levels across groups. However, triglyceride and high-density lipoprotein (HDL) levels showed significant increases in one group compared to the control, while low-density lipoprotein (LDL) levels remained unchanged. After 20 days, all lipid parameters showed no significant differences compared to the control group. These findings suggest that edible clay suspension may not substantially influence the lipid profile of pregnant rats over a short-term administration period.
