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With great economic and nutritional value, the banana and plantain are two of the most significant food crops in the world. However, the production of plantains and bananas in West Africa has been largely affected by a lack of sufficient healthy and uniform-sized planting materials. Techniques for rapidly multiplying these fruits in vitro and in vivo have been developed to solve the problem. Sword suckers from four Musa cultivars such as BITA 3, FHIA 18, FHIA 20, and Hex Ukiwe were used. This study evaluated the effects of mature coconut water (CW) and immature coconut water (CW) on axillary bud initiation, growth, and development of different species of plantain. The control was distilled water. The experiment was laid out in a 3×4 factorial completely randomized design. The sword suckers of each cultivar were scarified and disinfected with a mix of neem extract and fungicide. After air drying under a shade for 72 hours, they were planted in saw dust on January 2022 and covered with transparent plastic. About 10ml of each treatment were applied for 3 consecutive alternate days to the scarified corms with syringe. Results indicated that Coconut water (CW) significantly affected axillary bud initiation, growth, and development of banana and plantain in all morphological characteristics except No. of survived plantlets, there was a positive correlation between all characteristics with No. of leaves indicating significant positive character association with all other morphological characteristics.