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ABSTRACT
Anthocleista grandiflora is commonly used traditionally as herbal medicine and has been documented to have a broad range of therapeutic effects. This study was carried out to evaluate the effects of aqueous leaf extract of Anthocleista grandiflora on hematological indices of wistar rats. A total of twenty (20) male rats were used for this study. The animals were divided into four (4) groups; 1 - 4, with each group containing five (5) rats. Animals in group 1 were administered with distilled water and they served as control. Animals in group 2 – 4 were administered with different doses of the extract of Anthocleista grandiflora at dosage levels of 200mg/kg, 400 mg/kg, and 8000 mg/kg respectively. After twenty-eight (28) consecutive days of treatment, all the rats were sacrificed. Blood samples were collected in sample bottles for the evaluation of hematology levels. Hematology results showed that at all the extract dose levels studied were not significant ( P>0.05).
