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ABSTRACT This study examined the collection and transportation of municipal solid waste in Oshimili South Local Government Area of Delta State with a view of developing an effective solid waste collection and transportation systems for the area. This study would enhance the capacity of municipal solid waste managers in the collection and transportation of solid waste and offer a healthier living environment. The determination of the solid waste generation and density during this study we re done in accordance with United Nations Environment Programme (UNEP) guidelines and ASTM E1109 - 86 (2009) standard test method, which is based on mass-volume analysis method. The quantity of solid waste collected and transported per day in the study are a was estimated by using the density of solid waste and load carrying capacity (volume) of the waste trucks. The population of the study area was projected from the 2006 census figure of the Federal Republic of Nigeria. Field observation was used to collect data which include number of trip for each truck, waste collection crew size and the waste collection f requency in the study area. The cost of fuel, labour and vehicle maintenance were obtained through interview and questionnaire survey. Benefit-cost analysis of the solid waste collection and transportation system was estimated by using fuel cost, labour cost, maintenance cost, capital and depreciation costs of waste bins and trucks. A linear programming model was formulated for the study area in order to minimize the cost of collection and transportation of solid waste. The model was solved by using the Linear Program Solver, which is based on the ef ficient implementation of the modified simplex method that solves the large-scale problems. The results of this study showed that the total quantity of solid waste generated was 185,282.3kg/day, with an average waste generation rate of 0.82 kg/capita/day. The density of solid waste was 245.83kg/m3 and the total volume of solid waste collected per day was 429m3 which amount to 105,461.1kg. The waste collection rate was estimated at 57%, which revealed that the solid waste collection and transportation in the study area was inadequate. The result of the formulated linear programming model was N293,225. This result showed a reduction in the total solid waste collection and transportation costs per day by 36.8% compared to N464,273. The results of this study conform to the work of other researchers. An improved solid waste collection and transportation system was designed for the area and the benefit-cost ratio of the system resulted in a ratio of 1.6:1, indicating that the design is economically viable