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ABSTRACT
The triglyceride-glucose (TyG) index is an emerging marker of metabolic syndrome and insulin resistance, particularly relevant in the assessment of cardiovascular and metabolic risk. This study aimed to determine the TyG index in obese and overweight patients in Benin and evaluate its association with key anthropometric and biochemical parameters. A cross-sectional study was conducted among adults classified as overweight or obese based on body mass index (BMI) criteria. Fasting blood samples were collected to measure triglycerides and glucose levels, and the TyG index was calculated using the established formula. Anthropometric data, including BMI and waist circumference, were also obtained. The results revealed a significant correlation between the TyG index and anthropometric measures, particularly waist circumference, indicating its potential role in identifying central obesity-associated metabolic risks. Obese participants exhibited higher TyG indices compared to overweight individuals, suggesting an elevated risk of insulin resistance and cardiovascular complications in this population. The study highlights the utility of the TyG index as a simple, cost-effective biomarker for early detection of metabolic abnormalities in resource-limited settings. Further research is recommended to explore its prognostic value and intervention strategies to mitigate associated health risks in the Benin population.
