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ABSTRACT
This study extensively delves into the synthesis and antibacterial capabilities of CaO NPs derived from mango (mangifera leaves) extract. The synthesis underwent meticulous characterization through DLS, FTIR, EDX spectroscopy, providing intricate insights into the size, functional group and elemental composition of the nanoparticles respectively. Additionally, SEM facilitated a closer examination of the morphological features of the synthesized CaO NPs.The DLS results illuminated a nanoscale particle size of 61.47 nm, emphasizing the versatility of the synthesized nanoparticles for various applications. FTIR analysis precisely identified key functional groups and interactions, shedding light on the involvement of organic compounds from the mango leaves extract in the synthesis process. Furthermore, EDX analysis definitively confirmed the successful integration of calcium into the nanoparticles. SEM results further disclosed the surface tension of calcium oxide nanoparticles displaying undefined shapes with a certain degree of agglomeration.This study also examined the antibacterial potential of CaO NPs synthesized using mango leaves extract. Antibacterial assays were conducted against Klebsiella pneumoniae and Staphylococcus aureus, revealing concentration-dependent zones of inhibition for the CaO NPs. The minimum inhibitory concentrations determined were 0.6 mg/ml and 0.3 mg/ml for Klebsiella pneumoniae and Staphylococcus aureus, respectively. Comparative analyses with Ciprofloxacin, a conventional antibiotics for the treatment of a number of bacterial infection as control underscored the efficacy of CaO NPs. This study seamlessly integrated the synthesis and characterization of CaO NPs derived from mango leaves extract, unveiling their promising antibacterial applications and contributing insights into novel antibacterial agent development.