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ABSTRACT
The aim of this work is to test a plant extract for anticoagulation properties, thus its stability effect on blood minerals and proteins. This study focuses on attempting procedures for the use of glycosaminoglycan extracted from palm oil plants in the same proportion of standard heparin to achieve same effective results. A common problem in clinical laboratories is maintaining the stability of analytes over a period of time in blood banks or hematological sample bottles. The protein assayed includes albumin, total globulin, and total protein. The minerals assayed in this study are chloride ion, carbonate ion, potassium ion and sodium at temperature of 2°C -8°C. Blood samples were collected and anticoagulated with reference and test samples on Day 1, and screened for 4 weeks. Comparative evaluation of the differences in test and reference blood sample for protein and mineral stability in the blood show that the values were statistically insignificant (P > 0.05) and therefore clinically acceptable. This study successfully revealed the possibility of a plant based anticoagulant as an alternative to animal based heparin.
