ABSTRACT

One of the key factors contributing to the onset of type 2 diabetes mellitus and its consequences is inflammation. This study measured inflammatory markers (such as C-reactive protein) and uric acid in healthy and diabetic patients to investigate the relationship between inflammation and type 2 diabetes mellitus. Using keywords like diabetic mellitus, inflammatory indicators, and uric acid, relevant literature was found using the Google search engine, Pubmed, and journals. For sample collection and biochemical testing, the study was carried out at the University of Benin Teaching Hospital, UBTH, Benin City, Edo State. 70 people, split into two groups, participated in the study. The control group (30) and the diseased (diabetes) group (4o) were the two groups, respectively. Her control and diabetes status were confirmed by measuring her glycemic state. Enzyme-Linked Immunosorbent Assay (ELISA) was used to measure the inflammatory marker, and the photometric method was used to assess the uric acid. It was discovered that the experimental diabetic groups had lower levels of the inflammatory marker (C-reactive protein) than the control group. In conclusion, patients with non-diabetes mellitus subjects as opposed to diabetic subjects had considerably greater levels of the inflammatory marker (p 0.001) than patients with diabetes mellitus.