ASSESSMENT OF ANTIOXIDANT POTENTIALS OF ETHYL ACETATE STEM BARK EXTRACT

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ABSTRACT

Azanza garckeana, also known as "Snot Apple," is a plant species native to the tropical regions of Africa. The stem bark of A. garckeana has been traditionally used in African traditional medicine for its various medicinal properties. One of these properties is its potential antioxidant activity. Antioxidants are substances that can prevent or reduce oxidative damage to cells caused by free radicals. Free radicals are highly reactive molecules that can damage cells and contribute to the development of various diseases, including cancer, cardiovascular disease, and neurodegenerative diseases. Therefore, antioxidants are believed to play a protective role in the body by neutralizing these harmful molecules and helping to prevent or reduce oxidative stress. Several studies have investigated the antioxidant activity of A. garckeana stem bark. One study found that the stem bark extract of A. garckeana displayed strong antioxidant activity In-vitro, as measured by its ability to scavenge free radicals and inhibit lipid peroxidation. Other studies have also found that A. garckeana stem bark extract has a high total phenolic content, which is a measure of its antioxidant potential. In addition to its antioxidant activity, A. garckeana stem bark extract has also been shown to have anti-inflammatory, antibacterial, and cytotoxic effects. However, more research is needed to fully understand the medicinal properties of A. garckeana and to determine its potential use as a therapeutic agent. Overall, the stem bark of A. garckeana appears to have potent antioxidant activity and may have potential as a natural source of antioxidants for use in the prevention or treatment of oxidative stress-related diseases.

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