ABSTRACT

Emilia coccinea, have been reportedly used in the treatment of microbial infections and wounds. Hence, this study aim to assess the Antifungal Activity of the methanolic fraction of Emilia coccinea(sims) G.don. In order to confirm Emilia coccinea's alleged folkloric use in treating microbial illnesses, the assessment of the methanolic fraction of the whole plant was conducted. Sensitivity tests for antimicrobial properties of the methanolic fraction of Emilia coccinea were determined using the Agar well diffusion method. Minimum inhibitory Concentrations of the fraction was also determined using Agar dilution method. Commercial antifungal agent (ketoconazole) was used as the standard in the determination of the sensitivity of tested organisms.

The test organisms, such as Candida albicans, Aspergillus fumigates, Trichophyton rubrum, Rhodotorula glutinis, Microsporum audounii were found to be sensitive to the methanolic fraction. Rhodotorula glutinis showed the highest zone of inhibition of  21.25±0.78 mm. This findings show metanolic fraction of that E. coccinea plants possesses antifungal activity and may be a source of antifungal drugs. This justifies the plant's folkloric use in the treatment of microbiological infections.