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ABSTRACT
Urinary tract infection (UTI) is one of the most common infectious disease and the most common nosocomial infection in the developed world. The increasing resistance to therapeutically important antimicrobial agent (antibiotics) and the resent emergence of virulent and multidrug-resistant gene have made UTI management more challenging and difficult to treat. This research was carried out to determine the antibiotics resistance pattern and Gene expression of klebsiella pneumonia. From the descriptive analysis klebsiella pneumonia present in urine sample did not respond to antibiotics of azithromycin, erthromys in cefotataxime etc after antibiotics sensitive test. Further test for gene expression was done and gene confirm were the OXA,CIT and FOX gene which make up the subclass C and D of the B - lactamase gene, highly resistance to cehalosporin.
