ABSTRACT
This study delves into the effects of Adansonia digitata on the ratio of lymphocytes to white bloods cells in ovalbumin-induced asthma in guinea pigs. Adansonia digitata, a member of the Malvaceae family, is a native African tree commonly referred to as the African Baobab. It is widely distributed across arid savannah regions in Madagascar, mainland Africa, the Arabian Peninsula, and Australia, in Nigeria it is mostly found in the northern part of the country (Besco et al., 2007). It holds significant botanical, ethnobotanical, and pharmacological importance. Botanically, A. digitata is renowned for its ionic truck enabling it to thrive in arid environments. Ethanobotanically, it plays a crucial role in traditional medicine, food, and cultural practices across Africa. Pharmacologically, various parts of the baobab tree exhibit potent bioactivities, including antioxidant, antimicrobial, anti-inflammatory, and anti-diabetic properties (Smith, J. et al., 2024). Asthma is a chronic respiratory condition characterized by inflammation and narrowing of the airways, leading to coughing, chest tightness, and shortness of breath (Smith, J., & Johnson, A. 2023). Asthma is caused by a complex and incompletely understood environment and genetic interactions (Ho and Miller., 2008). These influence both its severity and its responsiveness to treatment (Borrell et al., 2007). Asthma can be attributable to atopy (Townshend et al., 2007), but factors unrelated to atopy can also be important in the development of the disease. Lymphocytes are a pivotal components of the human immune system, serving as key players in the body's defense against pathogens and foreign substances. Lymphocytes are a type of white blood cell, or leukocyte, and they play a central role in orchestrating immune responses and maintaining homeostatis.
