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ABSTRACT
Dilating drops are known as mydriatic drops because they contain active ingredients that dilates the pupil, thereby allowing for easy access to view posterior ocular structures. The elevation of intra ocular pressure has been reported to be associated with eyes in which the angle closes during mydriasis. This study was aimed at comparing the effect of two dilating drops, Vitrophen (5%) and Tropicamide (1%) on intra ocular pressure at intervals after instillation. A comprehensive check was conducted and sixty (60) subjects was selected after the evaluation of the anterior chamber angle depth with the use of the slit lamp, to ensure that they have grade 3 or 4 open angle, according to Shaffer's criteria. Baseline IOP measurement was taken and an average of three (3) readings was recorded for each subject. Subject that met the inclusion criteria was divided into two (2) groups. This experimental study was carried out on sixty (60) normotensive human subjects divided into two groups(n=30). Tropicamide (1%) was administered to the first group and Vitrophen (5%) was administered to the second group. This was done twice at a 10-minute interval. Result gotten was recorded and data extracted was analyzed using appropriate statistical methods. Dilating drops in evaluating the posterior part of the eye is frequently used in ocular examination and investigation. Therefore, this study was specifically aimed at determining the effect of these mydriatic drops: Tropicamide (1%) and Vitrophen (5%) on Intra ocular pressure (IOP).
KEYWORDS: Mydriatic drops, Dilating drops, Intraocular pressure.
